Ní hamháin go bhfuil an próiseas a bhaineann le artemisinin a shintéisiú go saorga casta, ach tá táirgeacht íseal agus tocsaineacht ard aige freisin. Dá bhrí sin, tá an soláthar reatha artemisinin ar an margadh a bhaintear go príomha as an ngléasra Artemisia annua. Áirítear ar na príomh-mhodhanna chun comhábhair ghníomhacha Artemisia annua a bhaint as decoction, eastóscadh aife, eastóscadh tuaslagóir orgánach, eastóscadh ultrasonaic, eastóscadh micreathonn agus eastóscadh supercritical CO2.
The reflux extraction method is one of the common methods for extracting plant active ingredients. Using ethanol as the organic solvent for reflux extraction is easy to operate, has high extraction rate, and does not pollute the environment. When using reflux extraction to extract active ingredients from plants, solvent concentration, solid-liquid ratio, extraction temperature, extraction time, etc. are important factors that affect extraction efficiency. Wang Lifang and other scholars have shown that the optimal extraction process conditions for the active ingredients of Artemisia annua are 55% ethanol concentration, 95°C extraction temperature, 2 h extraction time, and a solid-liquid ratio of 1:8, with ethanol concentration and extraction temperature being the main influencing factors. , extraction time and solid-liquid ratio are secondary influencing factors. In this experiment, ethanol was selected as the extraction solvent, and the ethanol concentration, solid-liquid ratio, extraction temperature, and extraction time for extracting the active ingredients of Artemisia annua were optimized. The results show that the order of factors in extracting active ingredients of Artemisia annua by reflux extraction is ethanol concentration>extraction temperature>solid-liquid ratio>Is é an t-am eastóscadh, agus paraiméadair an phróisis táirgthe is fearr ná tiúchan 65%, cóimheas soladach-leachtach de 1:8, Ba é an teocht eastósctha 80 céim agus ba é 4 h an t-am eastósctha, rud a bhí cosúil le torthaí staidéir roimhe seo.